Longevity, Senescence, and the Genome

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Longevity, Senescence, and the Genome

by: Caleb E. Finch

Topics include: obligate semelparity, mortality schedule data, clonai senescence, novo oogenesis, mortality rate coefficients, gradual senescence, genomic totipotency, reproductive scheduling, somatic cell proliferation, vegetatively reproducing organisms, genes with delayed adverse effects, postmitotic status, short adult phases, ovarian oocyte loss, transformational genetics, negligible senescence, statistical lifespan, clonal senescence, postnatal lifespan, postspawning survival, selective gene regulation, mortality rate parameters, oocyte stocks, glycated adducts, thirtyfold range

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First Sentence: This analysis of how the genome influences lifespan and senescence in higher organisms is based on species comparisons across many levels of biological organization.


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